Glioblastoma Testimonial – After 12 Months “no evidence of recurrence” – COC Protocol
K.W.’s quality of life has continued to improve since the initial surgery and radiation, reporting she feels stronger and stronger as the months pass. Last winter she was able to resume teaching ski lessons and playing hockey on her local team. Her latest MRI scan, performed on May 29th, shows no evidence of recurrence. One-year post diagnosis and she remains disease free! Read Her Story
See long term Glioblastoma survivors in the news who use the COC Protocol:
Patient 1 now 4 years out post diagnosis – Featured in The Telegraph
Patient 2 now 3 years out post diagnosis – Featured in Daily Mail
A clinical trial performed in the U.K., comprised of a 95-patient cohort, resulted in a median overall survival of 27 months when the COC Protocol was used in addition to standard-of-care. Compared to median overall survival of 15.6 months¹ and 14.8 months² with standard-of-care alone.
WHAT IS THE COC PROTOCOL?
The COC Protocol is an adjunctive cancer therapy comprised of a combination of well-established, FDA-approved medications. The medications are widely prescribed, with outstanding safety profiles. Research has demonstrated significant “off-target”, anti-cancer activity of the medications individually. For example, one medication in the protocol is a drug often prescribed for people with type 2 diabetes. Many studies have demonstrated the anti-cancer activity of this drug across most types of cancer.
WHY AREN’T THESE MEDICATIONS ALREADY BEING USED?
Mostly due to financial reasons. The medications comprising the COC Protocol are “off-patent”, therefore, pharmaceutical companies are unable to re-coup the cost necessary to win approval for a new indication. Putting these well-researched medications to use for cancer immediately presents much needed therapies to cancer patients with minimal side-effects. The COC protocol was conceived to finally realize the potential of these medicines in a thoughtful, responsible, and ethical manner. Starting in London in 2013, The COC Protocol has been safely administered to over 1400 patients by trained providers through a carefully monitored program.
WHAT ARE THE ADVANTAGES TO USING EXISTING MEDICATIONS?
The use of existing medications has several advantages, the most important being safety: Decades of clinical experience have documented the safety-profile, side-effects, and drug-drug interactions of the individual medications in the COC Protocol.
WHY USE A COMBINATION OF MEDICATIONS?
It is well-accepted that complex diseases like cancer respond better to combination therapies. The medications in the COC Protocol synergistically target cancer cells through a multitude of well-established mechanisms. In general, cancer cell’s pathological multiplication is the result of two processes: First, a breakdown of the normal signaling pathways that regulate cellular division. And second, unregulated energy metabolism that fuels the uncontrolled growth of cancer cells. The COC Protocol uniquely targets both processes. By starving cancer cells of energy substrates, the COC Protocol reduces the capacity of cancer cells to defend themselves against chemotherapy and radiation. The COC protocol also acts on the many dysregulated signaling pathways within cancer cells helping to enable a process called apoptosis, or “programmed cell death,” allowing chemotherapy and radiation to kill cancer cells more effectively. Finally, medications in the COC Protocol have been shown to operate by stimulating the immune system to fight your cancer by activating an important class of immune cells called Tumor Infiltrating Lymphocytes.
WHAT IS THE PROCESS FOR STARTING THE COC PROTOCOL?
