Paul Zhang, M.D., Ph.D

Paul Zhang, M.D., Ph.D. is the founder of the Institute of Integrative BioOncology (I2B). As a oncologist-scientist, he is board-certified in medical oncology and internal medicine and board-eligible for medical acupuncture. He has more than 10 years of clinical experience and has specialized in medical treatment of gastroenterological, lung, and prostate cancers. As a member of the Society of Integrative Oncology, he strongly advocates the application of evidence-based comprehensive and integrative approaches to treatment and health restoration. He was named as one of “America’s Top Physicians” in 2008.

Dr. Zhang is a well-known researcher and clinician in the areas of cancer stem cells, novel therapies, and solid tumors. He was among the first to define the growth requirements of cancer stem cells. He described the use of a novel class of drugs that induces cancer differentiation and cell death, histone deactylase (HDAC) inhibitors, and Zolinza (vorinostat) was the first FDA-approved HDAC inhibitor. His recent work focuses on the role of cancer stem cells in the response to novel drug combinations. He is a member of the Society of Integrative Oncology.

Dr. Zhang received his medical degrees from Hebei Medical University and Beijing University, was a resident oncologist at Columbia University, and a medical oncology fellow at Yale University. Dr. Zhang’s areas of and expertise include gastrointestinal (GI), lung. and prostate cancers. In his position, he works closely with other oncologists, including oncology surgeons, radiologists, and clinical investigators. He has presented his work at numerous national and international conferences. He is also the scientific director of the translational research at I2B where novel anti-cancer cocktails are being developed.

Expertise, experience, and dedication to quality matter a great deal to Dr. Zhang. He has been in community practice and academia for over 10 years, and innovation has become his lifelong passion. Cancer research has been the focus of his career.

Dr. Zhang has dedicated an additional 3 years to pursue a fellowship in cancer research at the world-renowned Memorial Sloan-Kettering Cancer Center in New York. His clinical and research interests include: solid tumor oncology, particularly colon, esophageal, gastric, pancreatic, prostate, and lung cancers. Other areas of expertise include: cancer immunotherapy; cancer stem cells; medical treatments, and acupuncture for pain management in cancer patients.

Education and Credentials

  • Clinical Fellowship: Yale University, New Haven, Connecticut
  • Cancer Research Fellowship: Memorial Sloan-Kettering Cancer Center, New York, NYInternal Medicine Residency: Columbia University, New York, NY
  • Medical Acupuncture Certificate: Helms Institute at Stanford Medical School, Stanford, CA

Former Assistant Professor of Medicine: Baylor College of Medicine, Houston, TX