COC Comment: New Research on COC Medications and NSAIDs

A large South Korean registry study has shown that the combination of two COC Protocol medications (metformin & statin) alongside aspirin reduced lung cancer incidence and mortality. The study also indicated that the potential for benefit increased the longer the duration of use –

Summary here
Full paper here

This is interesting as:

a) it adds to the research literature which suggests the combination of metformin and statin may exert synergistic anticancer effects (see, for example, recent papers in the context of Prostate and Endometrial cancer. Click to read more

b) it bolsters existing evidence on the potential usefulness of NSAIDs such as aspirin and ibuprofen in a cancer context. Click to read more